abstract：OBJECTIVE:To investigate practical patterns for stereotactic body radiotherapy to hepatocellular carcinoma in Korea. METHODS:In June 2013, the Korean Stereotactic Radiosurgery Group of the Korean Society for Radiation Oncology conducted a national patterns-of-care survey about stereotactic body radiotherapy to the liv...

journal_title：Japanese journal of clinical oncology

authors： Bae SH,Kim MS,Jang WI,Kay CS,Kim W,Kim ES,Kim JH,Kim JH,Yang KM,Lee KC,Chang AR,Jo S

更新日期：2016-04-01 00:00:00

abstract：:It is important to examine variation in the treatment effects of patients with esophageal cancer in order to generalize treatment outcomes. We aimed to investigate the range of prognostic differences among hospitals in the treatment of locally advanced esophageal cancer. The JCOG0303 study compared the efficacy of rad...

journal_title：Japanese journal of clinical oncology

authors： Hamamoto Y,Mizusawa J,Katayama H,Nakamura K,Kato K,Tsubosa Y,Ishikura S,Igaki H,Shinoda M,Fukuda H,Kitagawa Y,Ando N

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:ATPase family AAA domain-containing 2 plays an important role in tumor progression including cell cycle, proliferation, apoptosis and chemoresistance. However, the expression of ATPase family AAA domain-containing 2 in colorectal cancer and its significance are still unclear. The aim of this study was to exa...

journal_title：Japanese journal of clinical oncology

authors： Hou M,Huang R,Song Y,Feng D,Jiang Y,Liu M

更新日期：2016-03-01 00:00:00

abstract：:A thyroid ultrasound examination programme has been conducted in Fukushima Prefecture, Japan, after the nuclear disaster in 2011. Although remarkably high prevalence of thyroid cancer was observed, no relevant quantitative evaluation was conducted. We calculated the observed/expected (O/E) ratio of thyroid cancer prev...

journal_title：Japanese journal of clinical oncology

authors： Katanoda K,Kamo K,Tsugane S

更新日期：2016-03-01 00:00:00

abstract：:Trousseau's syndrome (cancer-associated thrombosis) is the second leading cause of death in cancer patients, after death from cancer itself. The risk of a venous thromboembolism is 4- to 7-fold higher in patients with cancer than in those without cancer. The causes of this impaired coagulation are associated with gene...

journal_title：Japanese journal of clinical oncology

authors： Ikushima S,Ono R,Fukuda K,Sakayori M,Awano N,Kondo K

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:There is little information about the patterns of care for elderly esophageal squamous cell carcinoma patients, and a standardized strategy has not been established. Therefore, we conducted a questionnaire survey about the patterns of care for these patients. METHODS:On September 2014, the questionnaires wer...

journal_title：Japanese journal of clinical oncology

authors： Hamamoto Y,Akutsu Y,Nagashima F,Hironaka S,Ito Y,Kato K,Hara H,Tsubosa Y,Nakagawa S,Daiko H,Ozawa S,Kitagawa Y

更新日期：2016-02-01 00:00:00

abstract：:Germline deletion of the 3' portion of the Epithelial Cell Adhesion Molecule (EPCAM) gene located 5' upstream of MutS Homolog 2 (MSH2) is a novel mechanism for its inactivation in Lynch syndrome. However, its contribution in Japanese Lynch syndrome patients is poorly understood. Moreover, somatic events inactivating t...

journal_title：Japanese journal of clinical oncology

authors： Eguchi H,Kumamoto K,Suzuki O,Kohda M,Tada Y,Okazaki Y,Ishida H

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Despite an increase in the number of Japanese patients with pancreatic neuroendocrine neoplasms, long-term outcomes and prognostic factors, especially for those with advanced disease, remain unclear. METHODS:We retrospectively reviewed the medical records of 78 patients with unresectable pancreatic neuroendo...

journal_title：Japanese journal of clinical oncology

authors： Lee L,Igarashi H,Fujimori N,Hijioka M,Kawabe K,Oda Y,Jensen RT,Ito T

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the association of molecular markers and conventional clinicopathological factors with bladder tumour recurrence in patients with primary upper tract urothelial carcinoma after radical nephroureterectomy. METHODS:The expressions of Ki-67 and P53 were measured by immunohistochemical staining prosp...

journal_title：Japanese journal of clinical oncology

authors： Wu P,Liu S,Zhang W,Zhang Y,Zhu G,Wei D,Wan B,Wang J

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Second primary malignancies have become the leading cause of death in retinoblastoma survivors. Although osteosarcoma is the most common second malignancy, little is known about its clinical and therapeutic features. METHODS:We retrospectively reviewed a database of patients with retinoblastoma and osteosarc...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara T,Fujiwara M,Numoto K,Ogura K,Yoshida A,Yonemoto T,Suzuki S,Kawai A

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:The estimated glomerular filtration rate is significantly decreased after nephroureterectomy. Deteriorating renal function likely affects the eligibility for cisplatin-based chemotherapy in patients with upper tract urothelial carcinoma. The present study was undertaken to identify preoperative factors for th...

journal_title：Japanese journal of clinical oncology

authors： Hashimoto T,Ohno Y,Nakashima J,Gondo T,Nakagami Y,Namiki K,Horiguchi Y,Yoshioka K,Ohori M,Tachibana M

更新日期：2015-11-01 00:00:00

abstract：:A randomized Phase III trial commenced in Japan in September 2014. Endoscopic local steroid injection has been commonly used and considered acceptable as the current standard treatment for the prevention of esophageal stricture after endoscopic submucosal dissection for superficial esophageal cancer. The purpose of th...

journal_title：Japanese journal of clinical oncology

authors： Mizutani T,Tanaka M,Eba J,Mizusawa J,Fukuda H,Hanaoka N,Takeuchi M,Aoyama I,Kojima T,Takizawa K,Ono H,Muto M,Gastrointestinal Endoscopy Study Group of the Japan Clinical Oncology Group (JCOG).

更新日期：2015-11-01 00:00:00

abstract：:Exciting recent advancements in deep-sequencing technology have enabled a rapid and cost-effective molecular characterization of patient-derived tumor samples. Incorporating these innovative diagnostic technologies into early clinical trials could significantly propel implementation of precision medicine by identifyin...

journal_title：Japanese journal of clinical oncology

authors： Bando H,Takebe N

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Fibulin-1 is a member of the fibulin gene family, characterized by tandem arrays of epidermal growth factor-like domains and a C-terminal fibulin-type module. Fibulin-1 plays important roles in a range of cellular functions including morphology, growth, adhesion and mobility. It acts as a tumor suppressor gen...

journal_title：Japanese journal of clinical oncology

authors： Cui Y,Liu J,Yin HB,Liu YF,Liu JH

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:The prognosis of breast cancer-derived brain metastasis is poor, but new drugs and recent therapeutic strategies have helped extend survival in patients. Prediction of therapeutic responses and outcomes is not yet possible, however. In a retrospective study, we examined prognostic factors in patients with bre...

journal_title：Japanese journal of clinical oncology

authors： Honda Y,Aruga T,Yamashita T,Miyamoto H,Horiguchi K,Kitagawa D,Idera N,Goto R,Kuroi K

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:Laminin-332, a marker of epithelial-mesenchymal transition, is composed of a heterotrimer of α3, β3 and γ2 chains that regulates cell adhesion and migration. This study aimed to disclose the respective clinical significance of laminin β3 immunoexpression in colorectal cancer as a prognostic factor and a predi...

journal_title：Japanese journal of clinical oncology

authors： Fukazawa S,Shinto E,Tsuda H,Ueno H,Shikina A,Kajiwara Y,Yamamoto J,Hase K

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Endobronchial ultrasound with a guide sheath has been a widely used diagnostic procedure for peripheral pulmonary lesions. After sequential sampling with the usual devices, small portions of the collected specimen remain in the guide sheath and these can potentially contribute to diagnosis. We assessed the di...

journal_title：Japanese journal of clinical oncology

authors： Izumo T,Sasada S,Chavez C,Matsumoto Y,Hayama M,Tsuchida T

更新日期：2015-04-01 00:00:00

abstract：:A case of advanced parotid cancer in which long-term control was achieved by superselective intra-arterial cisplatin infusion with concomitant radiotherapy is reported. A 63-year-old woman with parotid squamous cell carcinoma was referred to our hospital. Magnetic resonance images revealed extraparotid extension of th...

journal_title：Japanese journal of clinical oncology

authors： Kashiwagi N,Fujii T,Nishiyama K,Nakanishi K,Tomiyama N,Yagyu Y,Tsurusaki M,Kitano M,Murakami T

更新日期：2015-04-01 00:00:00

abstract：:The positive correlation between smoking and cancer risk is well estimated in sporadic colorectal cancer, whereas little is known with regard to Lynch syndrome-associated colorectal cancer. A total of 118 familial colorectal cancer patients from the Hereditary Nonpolyposis Colorectal Cancer Registry and Genetic Testin...

journal_title：Japanese journal of clinical oncology

authors： Tanakaya K,Furukawa Y,Nakamura Y,Hirata K,Tomita N,Tamura K,Sugano K,Ishioka C,Yoshida T,Ishida H,Watanabe T,Sugihara K,HNPCC registry and genetic testing project of the Japanese Society for Cancer of the Colon and Rectum.,Yama

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:This retrospective study analyzed the oncological and treatment outcomes of the patients with T1-T2N0 glottic cancer, who were treated with radiotherapy as initial treatment and salvaged by conservative surgery for radiation failure. METHODS:Between May 1999 and December 2010, 115 patients with glottic laryn...

journal_title：Japanese journal of clinical oncology

authors： Harada A,Sasaki R,Miyawaki D,Yoshida K,Nishimura H,Ejima Y,Kitajima K,Saito M,Otsuki N,Nibu K

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to evaluate the liver metastasis risk among colorectal cancer patients with liver cirrhosis. METHODS:This was a nationwide population-based cohort study of 2973 newly diagnosed colorectal cancer patients with liver cirrhosis and 11 892 age-sex matched controls enrolled in Taiwan betw...

journal_title：Japanese journal of clinical oncology

authors： Chiou WY,Chang CM,Tseng KC,Hung SK,Lin HY,Chen YC,Su YC,Tseng CW,Tsai SJ,Lee MS,Li CY

更新日期：2015-02-01 00:00:00

abstract：:Inguinal lymph node metastasis from adenocarcinoma arising at a colostomy site is extremely rare, and the significance of surgical resection for metastatic inguinal lymph nodes has not been established. An 82-year-old woman who had undergone abdominoperineal resection 27 years earlier was admitted to our hospital comp...

journal_title：Japanese journal of clinical oncology

authors： Iwamoto M,Kawada K,Hida K,Hasegawa S,Sakai Y

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To investigate the prognostic value of interleukin-11 receptor α chain in patients with early-stage clear-cell renal cell carcinoma. Interleukin-11 receptor α chain, a member of the gp130-dependent receptors, exerts pleiotropic oncogenic activities by promoting proliferation, angiogenesis and metastasis in ma...

journal_title：Japanese journal of clinical oncology

authors： Pan D,Xu L,Liu H,Zhang W,Zhu Y,Xu J,Gu J

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the correlations between the changes in the quality-of-life scores and the dose-volume histogram parameters in patients receiving high-dose-rate brachytherapy combined with hypofractionated external beam radiation therapy for localized prostate cancer. METHODS:Among the patients who were treated ...

journal_title：Japanese journal of clinical oncology

authors： Hashimoto Y,Akimoto T,Iizuka J,Tanabe K,Mitsuhashi N

更新日期：2015-01-01 00:00:00

abstract：:A randomized Phase II/III trial commenced in Japan in December 2013. Carboplatin plus etoposide is the current standard treatment for elderly extensive-disease small-cell lung cancer. The purpose of this study is to confirm the superiority of carboplatin plus irinotecan in terms of overall survival over carboplatin pl...

journal_title：Japanese journal of clinical oncology

authors： Eba J,Shimokawa T,Nakamura K,Shibata T,Misumi Y,Okamoto H,Yamamoto N,Ohe Y,Lung Cancer Study Group of the Japan Clinical Oncology Group.

更新日期：2015-01-01 00:00:00

abstract：:The proband was a 32-year-old man with sparse type of familial adenomatous polyposis with fundic gland and duodenal polyps and congenital hypertrophy of the retinal pigment epithelium without osteoma, dental abnormalities and desmoid tumors. Direct DNA sequencing did not detect germline mutations in any APC exon. Howe...

journal_title：Japanese journal of clinical oncology

authors： Yamaguchi T,Koizumi K,Arai M,Tamura K,Iijima T,Horiguchi S,Miyaki M

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:In this Phase 2 multicenter study the efficacy and safety of oral abiraterone acetate (1000 mg/once daily) plus prednisolone (5 mg/twice daily) was evaluated in metastatic castration-resistant prostate cancer patients from Japan who had previously received docetaxel-based chemotherapy. METHODS:Men (aged ≥20 ...

journal_title：Japanese journal of clinical oncology

authors： Satoh T,Uemura H,Tanabe K,Nishiyama T,Terai A,Yokomizo A,Nakatani T,Imanaka K,Ozono S,Akaza H

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Abiraterone acetate has been approved in >70 countries for chemotherapy-naïve metastatic castration-resistant prostate cancer patients. Efficacy and safety of abiraterone acetate (1000 mg/once daily) with prednisolone (5 mg/twice daily) in chemotherapy-naïve Japanese patients with metastatic castration-resist...

journal_title：Japanese journal of clinical oncology

authors： Matsubara N,Uemura H,Satoh T,Suzuki H,Nishiyama T,Uemura H,Hashine K,Imanaka K,Ozono S,Akaza H

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Most cancer patients become increasingly anxious toward the end of their life. The objective of this study was to identify predictors of increased opioid dosage in the last week of a terminal cancer patient's life. METHODS:We retrospectively reviewed charts of patients who died in our palliative care unit. W...

journal_title：Japanese journal of clinical oncology

authors： Miura T,Matsumoto Y,Motonaga S,Hasuo H,Abe K,Kinoshita H

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:We evaluated the feasibility of combination chemotherapy with paclitaxel, doxorubicin and cisplatin without prophylactic granulocyte colony-stimulating factor injection for intermediate-to-high-risk or recurrent endometrial cancer. METHODS:Women with histologically confirmed FIGO Stages I-II with >1/2 myomet...

journal_title：Japanese journal of clinical oncology

authors： Nagao S,Nishikawa T,Hanaoka T,Kurosaki A,Iwasa N,Hasegawa K,Fujiwara K

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:We sought to investigate general health status and late effects among adolescent and young adult survivors of childhood cancer. METHODS:We conducted a cross-sectional survey, using self-rated questionnaires on current and past health problems. Questionnaires were provided to childhood cancer survivors, a com...

journal_title：Japanese journal of clinical oncology

authors： Ozono S,Ishida Y,Honda M,Okamura J,Asami K,Maeda N,Sakamoto N,Inada H,Iwai T,Kamibeppu K,Kakee N,Horibe K

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus vaccines are being introduced worldwide and are expected to reduce the incidence of cervical cancer. Here we report a cross-sectional study using a validated human papillomavirus genotyping method to reveal the human papillomavirus prevalence and genotype distribution in Japanese women wi...

journal_title：Japanese journal of clinical oncology

authors： Azuma Y,Kusumoto-Matsuo R,Takeuchi F,Uenoyama A,Kondo K,Tsunoda H,Nagasaka K,Kawana K,Morisada T,Iwata T,Aoki D,Kukimoto I

更新日期：2014-10-01 00:00:00

abstract：:In seeking to understand how life-threatening illness affects children psychologically, projective testing may be beneficial, particularly when attempting to identify psychological problems in younger adolescents. The advantages of projective testing are that it does not depend on patients' verbal ability and is not i...

journal_title：Japanese journal of clinical oncology

authors： Hatano Y,Yamada M,Nakagawa K,Nanri H,Kawase M,Fukui K

更新日期：2014-10-01 00:00:00

abstract：:The Japan Public Health Center-based prospective Study conducted a baseline survey for 140 000 registered residents aged 40-69 years within 11 public health center areas nationwide in 1990-94. Five- and 10-year follow-up surveys were conducted to update information on lifestyle habits and health conditions. In total, ...

journal_title：Japanese journal of clinical oncology

authors： Tsugane S,Sawada N

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Endobronchial ultrasound-guided transbronchial needle aspiration is widely used for mediastinal and hilar lesions. Histologic specimens from this procedure are important for specific diagnosis and targeted therapy. Studies on the traditional endobronchial ultrasound-guided transbronchial needle aspiration nee...

journal_title：Japanese journal of clinical oncology

authors： Izumo T,Sasada S,Watanabe J,Chavez C,Matsumoto Y,Tsuchida T

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Overweight and obesity, indicated as increased body mass index, are associated with the risk of some cancers. We carried out a meta-analysis on published cohort and case-control studies to assess the strength of association between body mass index and gastric cancer. METHODS:Relevant studies were identified ...

journal_title：Japanese journal of clinical oncology

authors： Lin XJ,Wang CP,Liu XD,Yan KK,Li S,Bao HH,Zhao LY,Liu X

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:The optimal treatment for elderly patients with limited-disease small cell lung cancer has not been defined. We therefore performed a Phase I study for split-dose cisplatin plus etoposide combined with early concurrent accelerated hyperfractionated thoracic radiotherapy in elderly (70 years of age or older) p...

journal_title：Japanese journal of clinical oncology

authors： Okamoto K,Okamoto I,Takeda M,Kobayashi S,Takeda K,Nakamatsu K,Nishimura Y,Nakagawa K

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Emotional distress is considered to be higher in patients with head and neck cancer than other types of cancer. The present study aimed to identify predictors of the postoperative levels of depression in patients with head and neck cancer who have undergone surgery. METHODS:Postoperative levels of depression...

journal_title：Japanese journal of clinical oncology

authors： Adachi Y,Kimura H,Sato N,Nagashima W,Nakamura K,Aleksic B,Yoshida K,Fujimoto Y,Nakashima T,Ozaki N

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:There are few reports of the outcomes of external beam radiotherapy in Asian males with localized prostate cancer. The aim of this study is to evaluate the long-term outcomes of external beam irradiation using three-dimensional two-dynamic conformal arc therapy, combined with neoadjuvant hormonal therapy, in ...

journal_title：Japanese journal of clinical oncology

authors： Ikeda I,Mizowaki T,Norihisa Y,Takayama K,Kamba T,Inoue T,Nakamura E,Kamoto T,Ogawa O,Hiraoka M

更新日期：2014-02-01 00:00:00

abstract：:Monitoring the current status of cancer care is essential for effective cancer control and high-quality cancer care. To address the information needs of patients and physicians in Japan, hospital-based cancer registries are operated in 397 hospitals designated as cancer care hospitals by the national government. These...

journal_title：Japanese journal of clinical oncology

authors： Higashi T,Nakamura F,Shibata A,Emori Y,Nishimoto H

更新日期：2014-01-01 00:00:00